Every cell in the human body slowly produces d-ribose. Liver, fat tissue, and adrenal glands produce the highest levels to meet the production needs of hormones and fatty acids. Heart, brain, nerve, and skeletal muscle only make enough d-ribose to manage day-to-day needs during a normal state of health.
The body is not able to produce high levels of d-ribose quickly when under levels of stress, such as oxygen and blood deficiency connected to heart disease. Any time oxygen or blood flow is compromised the body tissues are not able to produce adequate levels of d-ribose, which leads to a depletion of cellular energy.
D-Ribose Deficiency
Characteristics of individuals at increased risk for a d-ribose deficiency include men and women over the age of 45 showing early signs of cardiac dysfunction, statin drug users, women with mitral valve prolapse, and individuals with high blood pressure and/or heart disease.