Posts tagged ‘research’

The Yale Heart Study Needs Study Participants

The Yale Heart Study is concerned with how people get medical care when they are having symptoms of a heart attack. They are asking people who have had a heart attack to share their experiences at their their website: http://heartstudy.yale.edu The goal of this study is to help people get care as quickly as possible when they are having heart attack symptoms.

The study is being conducted on the internet and takes about 30 minutes to an hour to complete depending on your experiences. Participation in this study is completely anonymous. The study has been approved by the Yale University Institutional Review Board and is funded by the National Institutes of Health. If you have any questions about this study please contact heart.study@yale.edu

If you know of someone who has had a heart attack, there is a place on the website for you to invite them to participate in the study.

Here’s the study address, again, is http://heartstudy.yale.edu

All the best,
Lisa Nelson RD
http://lisanelsonrd.com

Niacin–Statin Study Didn’t Give Desired Results: Stopped Early

The National Institutes of Health stopped a clinical trial studying a blood lipid treatment 18 months early. The study found that adding high dose, extended release niacin to statin treatment for patients with heart disease did not reduce cardiovascular events, such as heart attacks and strokes.

Study Participants

This study was referred to as AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health) and the 3414 participants were selected because they were at risk for cardiovascular events despite having a well controlled LDL cholesterol level. They were at increased risk due to a history of heart disease combined with low HDL cholesterol and high triglycerides. Low HDL levels and high triglycerides are both linked to increased risk of cardiovascular events.

Study participants were divided into two groups.

Continue reading ‘Niacin–Statin Study Didn’t Give Desired Results: Stopped Early’ »

Lower LDL Cholesterol and Live Longer

New results indicate individuals with low LDL cholesterol have a longer lifespan.

A study published in the Annals of Surgery and conducted at the University of Minnesota Medical School between 1975 and 2000 evaluated 838 heart attack survivors between the ages of 38-60 years-old. Out of the 838 participants 417 were instructed to go on a diet and 421 were instructed to diet combined with a partial ileal bypass surgery which bypasses the small intestine and location for cholesterol absorption. This is not a common surgery and typically reserved for high-risk heart attack patients who cannot tolerate statin medications. After 25 years, the participants in the second group had an increased life expectancy of one year.

Continue reading ‘Lower LDL Cholesterol and Live Longer’ »

Lower Cholesterol Effectively – Zetia Versus Niacin

It often feels like pharmaceutical companies often get wrapped up in dollar signs and forget the bottom-line reason for manufacturing the medication – improving your health. A study compared the effectiveness of Niacin versus Zetia.

The study

The study was published in the New England Journal of Medicine this past November 2009. Researchers analyzed the effect of extended-release niacin and ezetimibe (Zetia) on LDL cholesterol and HDL cholesterol levels.

Continue reading ‘Lower Cholesterol Effectively – Zetia Versus Niacin’ »

Lower Blood Pressure with a Low Carb Diet

Let me state right up front that I do not recommend following a low carb diet. That being said I want to share some of the latest research with you.

A study published on January 25, 2010 in the Archives of Internal Medicine compared a low carb diet versus a low fat plus orlistat diet. Researchers analyzed the effect of these two diets on weight loss and blood pressure.

Just in case you don’t know, orlistat is also known by the names Xenical and Alli.

Researchers studied 146 participants from the Department of Veterans Affairs primary care clinics in Durham, North Carolina. Participants were randomly assigned to either the low carb of the low fat plus orlistat diet, received instructions, and were monitored for 48 weeks. Some factors analyzed included body weight, blood pressure, fasting serum lipid, and glycemic parameters.

Results of the study found weight loss to be similar between the two groups at ~9% body weight. The low carbohydrate diet resulted in a lower blood pressure for participants when compared to the low fat diet with orlistat. The low carb diet lowered systolic (top number) blood pressure on average 5.9 mm Hg and diastolic (bottom number) blood pressure 4.5 mm Hg.

HDL Cholesterol and triglyceride levels improved for individuals on each diet, while LDL cholesterol improved only for those on the low fat plus orlistat diet. Glycemic parameters, such as glucose, insulin, and hemoglobin A1C only improved for low carbohydrate diet participants. Although it’s worth noting that the difference between groups was not statistically significant.

Like I said at the beginning I do not recommend a low carb diet. My first choice to promote a lower blood pressure would be the DASH diet. A study on the DASH diet was actually published in this same journal issue.

The DASH Diet alone was compared to the DASH diet in combination with a weight management and exercise plan. The DASH Diet when combined with an exercise/weight management plan resulted in an 11.2 mm Hg drop of systolic blood pressure and an average weight loss of 19 pounds over a 4 month period.

The main thing to remember is that you need to pick a plan you can stick with for the long term. Steady, consistent action is what will lead to results. If you haven’t already I encourage you to sign-up for the e-course 7 Natural Ways to Lower Blood Pressure at http://www.lowerbloodpressurewithlisa.com.

What do you think about using a low carb diet to lower blood pressure? Share your thoughts below.

All the best,
Lisa Nelson RD

Lower Blood Pressure – Does being a parent mean you have lower blood pressure?

You’d think the stress of raising children would cause blood pressure to boil; however, a study has actually found a link between parenthood and lower blood pressure, particularly in women. The Brigham Young Study monitored 198 adults for 24 hours. Seventy percent of participants had children, participants were married and in overall good health.

The study measured blood pressure using portable devices at random times throughout the day and night. Researchers found participants with children had an average blood pressure of 116/71 mm Hg. After factoring in other issues that impact blood pressure (i.e. age, gender, body mass index, and smoking, etc.) parents had a systolic (top number) blood pressure reading 4.5 points lower and a diastolic (bottom number) reading 3 points lower than participants without children. A greater difference was seen in women. Motherhood corresponded with a 12 point difference in systolic blood pressure and 7 point difference in diastolic blood pressure.

Interesting look at how not only dietary factors influence blood pressure. What do you think? Has being a parent had a positive impact on your blood pressure? Share your thoughts below!

Be sure to sign up for the free e-course 7 Natural Ways to Lower Blood Pressure at http://www.lowerbloodpressurewithlisa.com.

All the best,
Lisa Nelson RD

Saturated Fat Not Linked to Heart Disease – What Do You Think?

The latest research published in the American Journal of Clinical Nutrition found that saturated fat is not linked to heart disease as we’ve always be told. This latest study was a meta-analysis and did not find significant evidence linking dietary saturated fat with increased risk of heart disease.

A meta-analysis combines the results of several studies completed with similar theories. In this particular analysis, 21 studies were compared in regards to dietary fat and heart disease risk. I do like meta-analysis results, because they can provide a big picture look at the overall findings. However, there are weaknesses.

Here are three known weaknesses:

  1. Reliance on published studies – Studies that do not show significant results have difficulty getting published. If a meta-analysis only includes studies showing a positive or negative association there could be many unpublished studies finding no link.
  2. Studies included are not controlled – A meta-analysis may include studies with a poor design which can skew results inaccurately. The studies included in a meta-analysis is a subjective design made by the researchers – they get to decide.
  3. Simpson’s Paradox – This deals with statistics and how study results are interpreted. There are different ways to measure results and there is no one agreed upon measurement method – with is of particular importance in the field of medicine.

Why am I sharing this information with you?

Because the results of this latest meta-analysis are interesting, but I do not recommend you throw out your olive oil and replace it with lard. It’s likely saturated fat does not deserve the “bad rap” it has received; however, that doesn’t mean excess amounts are good. Everything comes back to moderation.

Please let me know what you think by adding a comment below.

All the best,
Lisa Nelson RD
Heart Healthy Tips
http://www.hearthealthmadeeasy.com

Supplements – How to Pick a “Whole Food” Supplement for Optimal Health

If you strive for optimal health, consider adding a whole food supplement to your daily regimen. However, you must be a savvy shopper to make sure you select a supplement that lives up to its claims. . .many are a waste of money! Things to look for:

1. Independent research – This means the company selling the product did not conduct the research.

2. Double blind, placebo controlled studies – This means neither the “patient” nor the doctor knew if they were taking the supplement or a sugar pill. Provides more reliable results.

3. Research that shows results – If the product claims to raise antioxidant levels and reduce high blood pressure then research studies need to back this up.

4. Publication in peer reviewed journals, such as The Journal of the American College of Cardiology or the Journal of Human Nutrition and Dietetics.

All the best,
Lisa Nelson RD
Juice Plus